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Scientific publications

We contribute to the research and dissemination of information about the bond between people and animals.

How Specific Ingredients contribute to dog’s and cat’s health

A Cat and a dog hugging

2005.- Oral supplemented YEAST NUCLEOTIDES IMPROVE THE IMMUNE STATUS OF PUPPIES AT WEANING. Romano et al (2007)

2006.- Polyphenols from CITRUS FRUIT and GREEN TEA in dogs improve antioxidant status and modulates gene expression: Torre et al (2006); Salas et al (2009); Mata-Bilbao et al (2007)

2006:- Immunoglobulines from porcine plasma can arrive active at dog & cat dog, and can contribute to gut health . Rodriguez et al (2007), Lynch A (2013)

2007.- Probiotic Lactobacilli bacteria has been isolated from bitche’s milk and evaluate their probiotic effect in vitro. Martin R et al (2010); Sanchez et al (2008)

2011.-Polyphenols from CITRUS FRUITS and CURCUMA improve antioxidant status and inflammatory markers in cats. Leray et al (2011), Jeusette et al (2010)

2011.- Herbal blend to control of gut parasitosis in dogs Salas et al (2012)

2013.- Hop Phytoestrogens are able to control food intake of sterilized cats, but not orally. Backus et al (2013)

2019.- SPIRULINE suplementation enhance vitality in dogs. Salas-Mani et al (2019)

2021.- CRANBERRY fruit helps to control pathogen bacteria in the urinary tract of dogs. Carvajal-Campos et al (2023)

2024.- CRANBERRY fruit helps to control pathogenic bacteria in the urinary tract of cats. Carvajal-Campos, A. et al (2024)

How diet contribute to skin barrier integrity

Close-up of a person grooming a dog

2006.- A canine skin equivalent has been developed to be used “in vitro” for screening dietary supplements with skin properties. Serra et al (2007)

2011.- A New management diet that contribute to control Canine Atopic dermatitis. Sanchez et al (2011)

Focus on sterilization

Close-up of a dog and cat sleeping together

2009.- Overweight increase oxidation and inflammatory markers in cats. Jeusette et al (2009)

2014.- The changes in Choline metabolism and hepatic lipid profile with sterilization have been analyzed. Valtolina et al (2015)

2014.- Effect of sterilization in activity and satiety related hormones in dogs. Schauf et al (2016) and (2017)

2015.- Long term effects of sterilization in body composition and blood markers in cats with high fat or high fiber diets. Jeusette et al (2017)

2022.- Sterilized cats in home fed ad libitum can maintain body weight with a balanced extruded diet with 38 % protein. Higher protein increase water turnover and activity. Goloni eta al (2024)

How diet affects Urinary Health

Close-up of a kitten in a litter box.

2016.- A urinary metabolic foot print for Feline urinay disease. Priymenko et al (2017)

2019.- A diet supplemented with fish peptides and L-tryptophan can help to reduce stress in cats. Jeusette et al (2021)

Improving dog & cat oral health

A photo of a person and a dog, the person is holding a toy while the dog plays with it and pulls on the toy with its mouth.

2010.-The more important oral pathogen bacteria involved in periodontal disease in cats had been identified. Perez-Salcedo et al (2011) & (2013) & (2015)

2015.- Feeding an dental treat in dogs effect in the next 24 h. Jeusette et al (2016)

2017.- Daily dental treat reduce tartar, plaque and halitosis in toy dogs. Mateo et al (2020)

Articular Care

Photo of a woman and a dog running together

2011.- Relation of vitamin K markers and Cartilage markers in osteoarthritis dogs. Salas-Mani et al (2012)

Improving wellbeing of dogs & cats with aging

A photo of a person lying on a couch, with a cat sitting on their chest.

2014.- Old cats have low levels vit B12 and low fat digestibility. Salas-Mani et al (2014)

2018.- Oral supplementation of vit B12 is effective in improving subnormal cobalaminaemia. Salas et al (2018)

2016.- Antioxidant status, cognitive performance and adaptation in aging dogs. Salas et al (2016)

2021.- How age impact in gut microbiota in dogs and cats. Fernandez-Pinteño et al (2024)

2025.- Age-related changes in dogs' gut health and behavior. Fernández-Pinteño, A. et al (2025)

2026.- A cognitive dysfunction rating scale for senior dogs. García, E. et al (2026)

Gut Microbiota & health

A photo of a dog eating from a bowl in the kitchen.

2017.- High fat diets affect negatively dogs gut microbiota. Schauf et al (2018)

2016.- Targeting Gut Microbiota for weight loss diets in dogs and cats. Salas-Mani et al (2018) and Jeusette et al (2018 and 2019)

2014.- Fermentable fibers supplementation can help to spare aminoacids in a low protein-diet. Wambacq et al (2016)

2021.- Supplemented diets with fibers from cereals or fruits modulate gut microbiome, digestion and immune status in dogs. Montserrat-Malagarriga et al (2024)

2022.- Supplemented diets with prebiotics, probiotics and fibers contribute to optimize gut microbiome in dogs. Montserrat-Malagarriga et al (2024)

2024.- Use of different combinations of prebiotics and probiotics to improve gut health in dogs. Montserrat-Malagarriga, M. et al (2024)

2024.- Supplementation with a prebiotic fibre modulates gut microbiota and immune response in cats. Jeusette, I. et al (2024)

2025.- A blend of probiotics, prebiotics and immunoglobulins for acute diarrhea in dogs. Jeusette, I. et al (2024)

Bibliography

  • García, E. et al. Which aspects of the everyday behavior of older dogs correlate with performance on a visuo-spatial memory test and the canine cognitive dysfunction rating scale (CCDR)? Front. Aging Neurosci. 18, 1678032 (2026).

  • Fernández-Pinteño, A. et al. Age-Related Changes in Gut Health and Behavioral Biomarkers in a Beagle Dog Population. Animals 15, 234 (2025).

  • Jeusette, I. et al. A new highly digestible prescription diet containing Bacillus velezensis DSM 15544, fructo-oligosaccharides, plasma immunoglobulin, yeast and sepiolite for the management of acute diarrhea in dogs—a randomized double-blinded, controlled trial. Front. Vet. Sci. 12, 1665730 (2025).

  • Carvajal-Campos, A. et al. The effect of consumption of cranberry (Vaccinium macrocarpon) on Escherichia coli adherence to feline uroepithelial cells in a blind randomised cross-over trial in cats. J. Vet. Res. 0, (2024).

  • Montserrat-Malagarriga, M. et al. Use of Different Synbiotic Strategies to Improve Gut Health in Dogs. Animals 14, 3366 (2024).

  • Jeusette, I. et al. Dietary Inulin Supplementation Modulates Fecal Microbiota and Vaccine Response in Cats—A Double-Blind Randomized Controlled Pilot Study. Pets 1, 485–499 (2024).

  • Goloni, C. et al. High starch intake favours bodyweight control in neutered and spayed cats living in homes fed ad libitum. Br. J. Nutr. 1–17 (2024).

  • Montserrat-Malagarriga, M. et al. The Impact of Fiber Source on Digestive Function, Fecal Microbiota, and Immune Response in Adult Dogs. Animals 14, 196 (2024).

  • Jeusette, I. et al. Dietary Inulin Supplementation Modulates Fecal Microbiota and Vaccine Response in Cats—A Double-Blind Randomized Controlled Pilot Study. Pets 1, 485–499 (2024).

  • Carvajal-Campos, A. et al. Adherence of uropathogenic Escherichia coli in dog urine after consumption of food supplemented with cranberry (Vaccinium macrocarpon). J. Vet. Res. 67, 49–54 (2023).

  • Jeusette, I. et al. Evaluation of a new prescription diet with lemon balm, fish peptides, oligofructose and L-tryptophan to reduce urinary cortisol, used as a marker of stress, in cats. J. Vet. Behav. 42, 30–36 (2021).

  • Mateo, A. et al. Evaluation of Efficacy of a Dental Chew to Reduce Gingivitis, Dental Plaque, Calculus, and Halitosis in Toy Breed Dogs. J. Vet. Dent. 37, 22–28 (2020).

  • Valtolina, C. et al. Sex specific differences in hepatic and plasma lipid profiles in healthy cats pre and post spaying and neutering: relationship with feline hepatic lipidosis. BMC Vet. Res. 13, 231 (2017).

  • Schauf, S. et al. Effect of sterilization and of dietary fat and carbohydrate content on food intake, activity level, and blood satiety–related hormones in female dogs. J. Anim. Sci. 94, 4239–4250 (2016).

  • Valtolina, C. et al. No up-regulation of the phosphatidylethanolamine N-methyltransferase pathway and choline production by sex hormones in cats. BMC Vet. Res. 11, 280 (2015).

  • Pérez-Salcedo, L. et al. Isolation and Identification of Porphyromonas spp. and other Putative Pathogens from Cats with Periodontal Disease. J. Vet. Dent. 30, 208–213 (2013).

  • Leray, V. et al. Curcuma or citrus extract supplementation does not improve body condition nor insulin sensitivity in obese cats. FASEB J. 24, 725.2-725.2 (2010).

  • Jeusette, I. et al. Effects of consuming diets containing various fats or citrus flavanones on plasma lipid and urinary F2-isoprostane concentrations in overweight cats. Am. J. Vet. Res. 71, 1039–1044 (2010).

  • Rodriguez, C. et al. Porcine immunoglobulins survival in the intestinal tract of adult dogs and cats fed dry food kibbles containing spray-dried porcine plasma (SDPP) or porcine immunoglobulin concentrate (PIC). Anim. Feed Sci. Tech. 139, 201–211 (2007).

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